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Ferulic acid

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Autophagy (1) Bcl-2 Family (3) Biochemical Assay Reagents (1) COX (1) Drug Metabolite (3) Endogenous Metabolite (11) Ferroptosis (3) FGFR (5) Isotope-Labeled Compounds (2) nAChR (1) NADPH Oxidase (1) NF-κB (1) p38 MAPK (1) Phosphatase (1) Reactive Oxygen Species (3) ROCK (1) β-catenin (3)
By Research Areas:	Cancer (12) Cardiovascular Disease (4) Infection (1) Inflammation/Immunology (2) Metabolic Disease (1) Neurological Disease (4)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Amino acid Transporter Amino Acid Derivatives Amino Acid Decarboxylase Hydroxycarboxylic Acid Receptor (HCAR) Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0060

Ferulic acid Maximum Cited Publications 8 Publications Verification Coniferic acid	FGFR Endogenous Metabolite	Cancer
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-147323

Ferulic acid 4-O-sulfate Ferulic acid 4-sulfate	Drug Metabolite	Cardiovascular Disease
Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice .

HY-N7715

Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside	Drug Metabolite	Others
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid (HY-N0060) . Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

HY-W018643

Ferulic acid methyl ester Methyl ferulate	p38 MAPK Autophagy	Neurological Disease Inflammation/Immunology Cancer
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-N0060A

Ferulic acid sodium Maximum Cited Publications 8 Publications Verification Coniferic acid sodium	FGFR Endogenous Metabolite Reactive Oxygen Species	Cardiovascular Disease Cancer
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W051164

5-Hydroxyvanillin	Endogenous Metabolite	Infection
5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves .

HY-147323R

Ferulic acid 4-O-sulfate (Standard) Ferulic acid 4-sulfate (Standard)	Drug Metabolite	Cardiovascular Disease
Ferulic acid 4-O-sulfate (Standard) is the analytical standard of Ferulic acid 4-O-sulfate. This product is intended for research and analytical applications. Ferulic acid 4-O-sulfate (Ferulic acid 4-sulfate) is a metabolite of Ferulic acid (HY-N0060). Ferulic acid 4-O-sulfate relaxes arteries and lowers blood pressure in mice[1].

HY-N0060R

Ferulic acid (Standard)	FGFR Endogenous Metabolite	Cancer
Ferulic acid (Standard) is the analytical standard of Ferulic acid. This product is intended for research and analytical applications. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N0060S1

Ferulic acid-13C3	Isotope-Labeled Compounds FGFR Endogenous Metabolite	Cancer
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N0060AR

Ferulic acid (sodium) (Standard)	FGFR Endogenous Metabolite Reactive Oxygen Species	Cardiovascular Disease Cancer
10-Deacetyltaxol (Standard) is the analytical standard of 10-Deacetyltaxol. This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .

HY-N3894

Ferulamide	nAChR	Neurological Disease
Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities .

HY-N0060BR

*(E)-Ferulic* acid (Standard)**	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid (Standard) is the analytical standard of (E)-Ferulic acid. This product is intended for research and analytical applications. (E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N0060B

*(E)-Ferulic* acid** (E)-Coniferic acid	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-139715

IMD-ferulic	NF-κB	Cancer
IMD-ferulic is a covalently linked NF-κB modulator that improves the adjuvanticity of small molecule immune potentiators.

HY-N11516

*Erythro-guaiacylglycerol-β-ferulic* acid ether**	Others	Others
Erythro-guaiacylglycerol-β-ferulic acid ether is a natural product that can be isolated from Gueldenstaedtia verna .

HY-N0060BS

*(E)-Ferulic* acid-d3** (E)-Coniferic acid-d₃	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite	Cancer
(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

HY-W018643A

*(E)-Ferulic* acid methyl ester** Methyl (E)-ferulate	COX	Others
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N11441

*cis-Ferulic* acid 4-O-β-D-glucopyranoside**	Phosphatase	Metabolic Disease
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B .

HY-145294

ROCK2-IN-5	ROCK	Neurological Disease
ROCK2-IN-5 (compound 1d) is a hybrid compound containing structural fragments of the Rho kinase inhibitor fasudil and the NRF2 inducers caffeic and ferulic acids. ROCK2-IN-5 has good multitarget profile and good tolerability. ROCK2-IN-5 has the potential for thr research of Amyotrophic lateral sclerosis (ALS) with a SOD1 mutation .

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol Ferulic acid ester	NADPH Oxidase	Inflammation/Immunology Cancer
Cycloartenyl ferulate (Cycloartenol ferulate) is one of the typical triterpene alcohols and possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities .

HY-W005288

4-Vinylphenol (10% in Propylene glycol) 4-Hydroxystyrene	Apoptosis Endogenous Metabolite	Cancer
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N0061

Ethyl ferulate 1 Publications Verification	Reactive Oxygen Species	Neurological Disease
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

HY-W127505S

trans-2-Undecenal-d5	Biochemical Assay Reagents Isotope-Labeled Compounds	Others
trans-2-Undecenal-d₅ is deuterated labeled 4-Vinylphenol (HY-W005288). 4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-P2875

Hemicellulase	Endogenous Metabolite	Others
Hemicellulase is a hemicellulose-targeting hydrolase that breaks down the binding of glucose and polymers to water molecules present in plant fibers. Hemicellulase specifically degrades hemicellulose (such as xylan and mannan) in plant cell walls by hydrolyzing β-1,4-xylosidic bonds and ester bonds (such as acetyl and ferulic acid ester bonds). Hemicellulase relies on the synergistic action of the glycoside hydrolase (GH) and carbohydrate esterase (CE) families to achieve efficient hydrolysis through acid-base catalysis (such as Glu/Asp residues) and substrate binding pockets. Hemicellulase can be used in the food industry (such as improving bread texture)， biofuel production (lignocellulose pretreatment) and paper industry (biobleaching) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0060

Ferulic acid Maximum Cited Publications 8 Publications Verification Coniferic acid	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols other families Simple Phenylpropanols Sunscreen Phenols Phenylpropanoids Cosmetic Research Disease Research Fields Cancer	FGFR Endogenous Metabolite
Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N7715

Ferulic acid acyl-β-D-glucoside Ferulic acid glucoside	Monophenols Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Rosaceae Phenols Phenylpropanoids Plants Aruncus sylvester Kostel. Disease Research Fields	Drug Metabolite
Ferulic acid acyl-β-D-glucoside is a metabolite of Ferulic Acid (HY-N0060) . Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively .

HY-W018643

Ferulic acid methyl ester Methyl ferulate	Monophenols Classification of Application Fields Neurological Disease Simple Phenylpropanols Stemonaceae Source classification Phenols Phenylpropanoids Plants Disease Research Fields Stemona tuberosa Lour. Cancer	p38 MAPK Autophagy
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-N0060A

Ferulic acid sodium Maximum Cited Publications 8 Publications Verification Coniferic acid sodium	Structural Classification Monophenols other families Classification of Application Fields Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Endogenous metabolite Disease Research Fields Cancer	FGFR Endogenous Metabolite Reactive Oxygen Species
Ferulic acid sodium is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC₅₀s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W051164

5-Hydroxyvanillin	Infection Structural Classification Classification of Application Fields Source classification Phenols Polyphenols Endogenous metabolite Disease Research Fields	Endogenous Metabolite
5-Hydroxyvanillin is the product of the bacterial and fungal breakdown of ferulic acid, an abundant component in cell walls of found in many seed and leaves .

HY-N0060B

*(E)-Ferulic* acid** (E)-Coniferic acid	Structural Classification Classification of Application Fields Source classification Plants Endogenous metabolite Human Gut Microbiota Metabolites Monophenols Microorganisms other families Simple Phenylpropanols Phenols Phenylpropanoids Disease Research Fields Cancer	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite
(E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N0060R

Ferulic acid (Standard)	Structural Classification Human Gut Microbiota Metabolites Monophenols other families Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Endogenous metabolite	FGFR Endogenous Metabolite
Ferulic acid (Standard) is the analytical standard of Ferulic acid. This product is intended for research and analytical applications. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-N0060AR

Ferulic acid (sodium) (Standard)	Structural Classification Monophenols other families Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Endogenous metabolite	FGFR Endogenous Metabolite Reactive Oxygen Species
10-Deacetyltaxol (Standard) is the analytical standard of 10-Deacetyltaxol. This product is intended for research and analytical applications. 10-Deacetyltaxol (10-Deacetylpaclitaxel) is a taxane derivative isolated from Taxus wallichiana Zucc . 10-Deacetyltaxol (10-Deacetylpaclitaxel) promotes the polymerization of tubulin and to inhibit the depolymerization of microtubules induced by cold or by calcium ions in vitro . 10-Deacetyltaxol (10-Deacetylpaclitaxel) exhibits cytotoxicity in human glial and neuroblastoma cell-lines .

HY-N3894

Ferulamide	Alkaloids Monophenols Source classification Phenols Plants Umbelliferae Carphephorus corymbosus (Nutt.) Torr. & A.Gray	nAChR
Ferulamide is a Ferulic acid derivative isolated from Portulaca oleracea L. with anticholinesterase activities .

HY-N0060BR

*(E)-Ferulic* acid (Standard)**	Structural Classification Human Gut Microbiota Metabolites Monophenols Microorganisms other families Simple Phenylpropanols Source classification Phenols Phenylpropanoids Plants Endogenous metabolite	β-catenin Bcl-2 Family Ferroptosis Endogenous Metabolite
(E)-Ferulic acid (Standard) is the analytical standard of (E)-Ferulic acid. This product is intended for research and analytical applications. (E)-Ferulic acid is an isomer of ferulic acid, an aromatic compound abundant in plant cell walls. (E)-Ferulic acid causes phosphorylation of β-catenin (β-catenin), leading to proteasome degradation, increasing the expression of pro-apoptotic factor Bax and reducing pro-apoptotic factor Expression of the survival factor survivin. (E)-Ferulic acid can effectively remove reactive oxygen species (ROS) and inhibit lipid peroxidation. (E)-Ferulic acid exerts antiproliferative and antimigratory effects in the human lung cancer cell line H1299.

HY-N11516

*Erythro-guaiacylglycerol-β-ferulic* acid ether**	Other Terpenoids Structural Classification Leguminosae Terpenoids Source classification Plants Gueldenstaedtia verna (Georgi) Boriss.	Others
Erythro-guaiacylglycerol-β-ferulic acid ether is a natural product that can be isolated from Gueldenstaedtia verna .

HY-W018643A

*(E)-Ferulic* acid methyl ester** Methyl (E)-ferulate	Structural Classification Monophenols Ginkgoaceae Classification of Application Fields Simple Phenylpropanols Source classification Other Diseases Phenols Phenylpropanoids Plants Ginkgo biloba Disease Research Fields	COX
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) exhibits strong DPPH and ABTS ⁺ radical scavenging activities .

HY-N11441

*cis-Ferulic* acid 4-O-β-D-glucopyranoside**	Structural Classification Ketones, Aldehydes, Acids Zygophyllaceae Source classification Plants Nitraria sibirica Pall	Phosphatase
cis-Ferulic acid 4-O-β-D-glucopyranoside (compound 7) is a phenolic glycosid, which can be isolated from Nitraria sibirica.. cis-Ferulic acid 4-O-β-D-glucopyranoside exhibits antioxidant activity and potent inhibitory effect on Phosphatase PTP1B .

HY-125938

Cycloartenyl ferulate 1 Publications Verification Cycloartenol ferulate; Cycloartenol Ferulic acid ester	Triterpenes Structural Classification Monophenols other families Classification of Application Fields Terpenoids Source classification Phenols Plants Inflammation/Immunology Disease Research Fields	NADPH Oxidase
Cycloartenyl ferulate (Cycloartenol ferulate) is one of the typical triterpene alcohols and possesses several biological activities including anti-oxidative activity, antiallergic activity, anti-inflammatory and anticancer activities .

HY-W005288

4-Vinylphenol (10% in Propylene glycol) 4-Hydroxystyrene	Structural Classification Monophenols Microorganisms Classification of Application Fields Source classification Rubiaceae Phenols Plants Endogenous metabolite Disease Research Fields Hedyotis diffusa Willd. Cancer	Apoptosis Endogenous Metabolite
4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

HY-N0061

Ethyl ferulate 1 Publications Verification	Structural Classification Monophenols Simple Phenylpropanols Source classification Phenols Dicerothamnus rhinocerotis Phenylpropanoids Umbelliferae Plants	Reactive Oxygen Species
Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from Rhizoma Chuanxiong, induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress . Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity .

Cat. No.	Product Name	Chemical Structure

HY-N0060BS

*(E)-Ferulic* acid-d3**
(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

(E)-Ferulic acid-d3

(E)-Ferulic acid-d₃ is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pro-survival factor survivin. (E)-Ferulic acid shows a potent ability to remove reactive oxygen species (ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lung cancer cell line H1299[1].

HY-N0060S1

Ferulic acid-13C3
Ferulic acid- ¹³C₃ is the ¹³C-labeled Ferulic acid. Ferulic acid is a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor with IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.

HY-W127505S

trans-2-Undecenal-d5
trans-2-Undecenal-d₅ is deuterated labeled 4-Vinylphenol (HY-W005288). 4-Vinylphenol is found in the medicinal herb Hedyotis diffusa Willd, wild rice and is also the metabolite of p-coumaric and ferulic acid by lactic acid bacteria in wine. 4-Vinylphenol induces apoptosis and inhibits blood vessels formation and suppresses invasive breast tumor growth in vivo .

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Ferulic acid

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